Lipid sub-fractionation predicts worsening myocardial perfusion reserve in patients with low-density lipoprotein less than 100mg/dL: a regadenoson dardiac magnetic resonance study
نویسندگان
چکیده
Background Abnormalities in total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), and triglycerides (TG) are associated with microvascular dysfunction and are the primary target for treating atherosclerosis. Newer lipid assays allow for measurements of lipoprotein sub-fractions; however, their impact on microvascular function remain unknown. We sought to determine, in patients with LDL <100mg/dL, if abnormalities in lipid sub-fractionation are associated with reduced myocardial perfusion reserve (MPRi; a surrogate for microvascular dysfunction).
منابع مشابه
A vasodilator stress MRI perfusion study: large HDL particle number is independently associated with microvascular function in patients with LDL-C <100mg/dL
Background Abnormalities in total cholesterol (TC), high-density lipoprotein (HDL-C), low-density lipoprotein (LDL-C), and triglycerides (TG) are associated with microvascular dysfunction. Recent studies suggest that lipoprotein sub-fractions better predict atherogenic burden than a routine lipid panel. We sought to determine, whether lipid sub-fractionation is associated with myocardial perfus...
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